Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23299517 | 0.76 | GRM2 (0.43) | F10TNKSKDM1AMAOAMAOB | |
| SCHEMBL350826 | 0.73 | KDM1A (0.41) | F10TNKSKDM1AMAOAMAOB | |
| SCHEMBL23270156 | 0.73 | MEN1 (0.47) | OPRM1ALDH1A1 | |
| SCHEMBL1377738 | 0.72 | KDM1A (0.46) | F10TNKSALDH1A1GAAKDM1A | |
| SCHEMBL2535612 | 0.71 | DGAT1 (0.51) | TNKSKDM1AMAOAMAOBRCOR1 | |
| SCHEMBL1455890 | 0.71 | BCL2 (0.48) | F10TNKSALDH1A1KDM1AMAOA | |
| SCHEMBL2535607 | 0.71 | TNKS (0.45) | F10TNKSKDM1AMAOAMAOB | |
| SCHEMBL13167913 | 0.71 | HSD11B1 (0.47) | F10TNKSKDM1AMAOAMAOB | |
| SCHEMBL2646792 | 0.71 | KDM1A (0.45) | F10TNKSKDM1AMAOAMAOB | |
| SCHEMBL29348761 | 0.71 | TNKS (0.45) | F10TNKSKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |