Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | IGF2R | P11717 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609482 | 0.87 | MAPT (0.41) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6609487 | 0.87 | MAPT (0.41) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6606537 | 0.85 | PDE4B (0.34) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6606002 | 0.83 | MAPT (0.41) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6611313 | 0.80 | EGFR (0.45) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6611309 | 0.80 | EGFR (0.45) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6610871 | 0.79 | MAPT (0.44) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6610876 | 0.79 | MAPT (0.44) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6606526 | 0.79 | PDE4B (0.42) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6606520 | 0.79 | PDE4B (0.42) | MAPTMEN1KMT2AATMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |