Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.34 |
| ▸ | PDE4A | P27815 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | IGF2R | P11717 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606520 | 0.89 | PDE4B (0.42) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6606526 | 0.89 | PDE4B (0.42) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6606341 | 0.85 | MAPT (0.37) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6607496 | 0.84 | PDE4B (0.37) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6609487 | 0.80 | MAPT (0.41) | MAPTKDM4ENPSR1ALDH1A1TDP1 | |
| SCHEMBL6609482 | 0.80 | MAPT (0.41) | MAPTKDM4ENPSR1ALDH1A1TDP1 | |
| SCHEMBL6608561 | 0.79 | PDE4B (0.33) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6607423 | 0.79 | KDM4E (0.40) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6607425 | 0.79 | KDM4E (0.40) | PDE4BPDE4AMAPTPDE4CPDE4D | |
| SCHEMBL6611092 | 0.76 | PDE4D (0.43) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |