Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | IGF2R | P11717 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611390 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6611396 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6607496 | 0.85 | PDE4B (0.37) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6611008 | 0.84 | SMN1; SMN2 (0.38) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6606341 | 0.83 | MAPT (0.37) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6607800 | 0.81 | EGFR (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6607790 | 0.81 | EGFR (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6609089 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6609083 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2AATMEGFR | |
| SCHEMBL6612839 | 0.80 | PDE4B (0.41) | MAPTMEN1KMT2AATMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |