Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606444 | 1.00 | EGFR (0.44) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607901 | 0.90 | SMN1; SMN2 (0.46) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607907 | 0.90 | SMN1; SMN2 (0.46) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6611008 | 0.89 | SMN1; SMN2 (0.38) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607249 | 0.87 | PDE4A (0.40) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607238 | 0.87 | PDE4A (0.40) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607093 | 0.87 | SMN1; SMN2 (0.43) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6607099 | 0.87 | SMN1; SMN2 (0.43) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6609196 | 0.87 | MAPT (0.43) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6609189 | 0.87 | MAPT (0.43) | EGFRSMN1; SMN2RECQLHIF1APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |