⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901150 | 0.78 | — | — | |
| SCHEMBL5724756 | 0.78 | — | — | |
| SCHEMBL10751495 | 0.77 | NOS1 (0.32) | — | |
| SCHEMBL128494 | 0.75 | — | — | |
| SCHEMBL10773497 | 0.74 | CYP3A4 (0.38) | — | |
| SCHEMBL2853189 | 0.74 | — | — | |
| SCHEMBL278457 | 0.74 | — | — | |
| SCHEMBL440250 | 0.74 | — | — | |
| SCHEMBL20503389 | 0.73 | PDE4B (0.31) | — | |
| SCHEMBL28204887 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1237054-C | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2006-01-18 | — | — | CN | claimed |
| CN-1399515-A | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2003-02-26 | — | — | CN | claimed |
| EP-0483851-B1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | MITSUBISHI CHEM CORP (JP) | 1996-03-13 | — | — | EP | claimed |
| EP-0433899-B1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | MITSUBISHI CHEM CORP (JP) | 1995-04-12 | — | — | EP | claimed |
| US-5128350-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-07 | — | — | US | claimed |
| EP-0483851-A1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | Mitsubishi Chemical Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| US-5055477-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES, USEFUL AS SYSTEMIC FUNGICIDES FOR PLANT AND MATERIAL PROTECTION | MITSUBISHI KASEI CORPORATION (JP) | 1991-10-08 | — | — | US | claimed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | claimed |
| CN-115244043-B | Benzimidazolone cinnamamide derivatives as TRPV1 antagonists and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4095133-B1 | BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT | JMACKEM CO LTD (KR) | 2024-07-24 | — | — | EP | disclosed |
| US-20230147428-A1 | BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT | JMACKEM CO., LTD (KR) | 2023-05-11 | — | — | US | disclosed |
| EP-4095133-A1 | BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT | Jmackem Co., Ltd (KR) | 2022-11-30 | — | — | EP | disclosed |
| CN-115244043-A | Benzimidazolonyl cinnamamide derivative as TRPV1 antagonist and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2022-10-25 | — | — | CN | disclosed |
| WO-2021215656-A1 | BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT | 주식회사 제이맥켐 (KR) | 2021-10-28 | — | — | WO | disclosed |
| US-5055477-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES, USEFUL AS SYSTEMIC FUNGICIDES FOR PLANT AND MATERIAL PROTECTION | MITSUBISHI KASEI CORPORATION (JP) | 1991-10-08 | — | — | US | disclosed |
| US-5055477-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES, USEFUL AS SYSTEMIC FUNGICIDES FOR PLANT AND MATERIAL PROTECTION | MITSUBISHI KASEI CORPORATION (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| US-4431441-A | PLANT GROWTH REGULATORS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-02-14 | — | — | US | disclosed |