⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751495 | 0.82 | NOS1 (0.32) | — | |
| SCHEMBL128494 | 0.80 | — | — | |
| SCHEMBL2853189 | 0.78 | — | — | |
| SCHEMBL278457 | 0.78 | — | — | |
| SCHEMBL6009809 | 0.78 | — | — | |
| Carbamic Acid SCHEMBL28884232 | 0.76 | NOS1 (0.32) | — | |
| SCHEMBL27605628 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL5828609 | 0.75 | NOS1 (0.33) | — | |
| SCHEMBL16861454 | 0.74 | NOS1 (0.37) | — | |
| SCHEMBL11034901 | 0.74 | ELANE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101585811-B | Pyrazole carbamate genus compound containing alkynes aryl as well as preparation method and application thereof | UNIV SOUTH CHINA AGRICULT | 2012-01-04 | — | — | CN | claimed |
| CN-101585811-A | Pyrazole carbamate genus compound containing alkynes aryl as well as preparation method and application thereof | UNIV SOUTH CHINA AGRICULT (CN) | 2009-11-25 | — | — | CN | claimed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | claimed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | claimed |
| US-20250171405-A1 | PYRAZOLYL COMPOUNDS AS KV7 CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD (US) | 2025-05-29 | — | — | US | disclosed |
| US-12209072-B2 | Cyclopentyl acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-01-28 | — | — | US | disclosed |
| EP-4482487-A1 | PYRAZOLYL COMPOUNDS AS KV7 CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (US) | 2025-01-01 | — | — | EP | disclosed |
| CN-112041302-B | Pyrazole O-linked carbamoyl cyclohexyl acids as LPA antagonists | 百时美施贵宝公司 | 2024-11-19 | — | — | CN | disclosed |
| US-11980609-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| EP-4337641-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117295717-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023164538-A1 | PYRAZOLYL COMPOUNDS AS KV7 CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2023-08-31 | — | — | WO | disclosed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | disclosed |
| WO-1997027180-A1 | ASPARTYL PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1997-07-31 | — | — | WO | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-4673429-A | Nitrification-inhibiting 1-hydroxypyrazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | US | disclosed |
| EP-0043798-A1 | Pyrazolyl carbamates and their use as pesticides | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |
| EP-0043798-A1 | Pyrazolyl carbamates and their use as pesticides | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |