Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 8/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SDHA | P31040 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743242 | 0.82 | CALML3 (0.44) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6685146 | 0.80 | CALML3 (0.57) | CALML3KCNH2MAOAMAOBLMNA | |
| SCHEMBL6685151 | 0.80 | CALML3 (0.57) | CALML3KCNH2MAOAMAOBLMNA | |
| SCHEMBL6608322 | 0.80 | F10 (0.46) | CALML3KCNH2MAOAMAOBLMNA | |
| SCHEMBL6607578 | 0.80 | F10 (0.46) | CALML3KCNH2MAOAMAOBLMNA | |
| SCHEMBL5738529 | 0.80 | GRM2 (0.35) | CALML3MAOAMAOB | |
| SCHEMBL5738634 | 0.78 | CALML3 (0.40) | CALML3MAOAMAOB | |
| SCHEMBL6608964 | 0.77 | CALML3 (0.42) | CALML3KCNH2MAOAMAOBLMNA | |
| SCHEMBL4766697 | 0.76 | GRM2 (0.45) | CALML3MAOA | |
| SCHEMBL6612683 | 0.75 | MAOA (0.63) | KCNH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |