Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | CALML3 | P27482 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533776 | 0.83 | CALML3 (0.47) | GRM2CALML3MAOAMAOB | |
| SCHEMBL5533771 | 0.83 | CALML3 (0.47) | GRM2CALML3MAOAMAOB | |
| SCHEMBL5531273 | 0.80 | GRM2 (0.40) | GRM2CALML3 | |
| SCHEMBL5531268 | 0.80 | GRM2 (0.40) | GRM2CALML3 | |
| SCHEMBL6606701 | 0.80 | CALML3 (0.40) | CALML3MAOAMAOB | |
| SCHEMBL5531671 | 0.78 | GRM2 (0.39) | GRM2 | |
| SCHEMBL5531661 | 0.78 | GRM2 (0.39) | GRM2 | |
| SCHEMBL5523064 | 0.77 | ABCB11 (0.48) | CALML3MAOAMAOB | |
| SCHEMBL5519710 | 0.77 | MAOA (0.53) | MAOAMAOB | |
| SCHEMBL5739114 | 0.76 | MAOA (0.38) | CALML3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654259-A1 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005005420-A1 | CYCLOPROPYL GROUP SUBSTITUTED OYAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |