Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607132 | 0.74 | ALDH1A1 (0.55) | CNR1HTR2CALDH1A1HPGDRAB9A | |
| SCHEMBL3878040 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HPGDRAB9AMAPTKDM4E | |
| SCHEMBL773987 | 0.71 | LCK (0.50) | CNR1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL27562376 | 0.64 | RAB9A (0.64) | ALDH1A1HPGDRAB9AMAPTKDM4E | |
| SCHEMBL25368842 | 0.64 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL27917675 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13779957 | 0.64 | HTR2C (0.55) | CNR1HTR2CALDH1A1HPGDMAPT | |
| SCHEMBL3589407 | 0.63 | ALDH1A1 (0.54) | CNR1HTR2CALDH1A1HPGDMAPT | |
| SCHEMBL6619760 | 0.63 | ALDH1A1 (0.38) | ALDH1A1RAB9AMAPTNPC1KMT2A | |
| SCHEMBL3317728 | 0.62 | SIGLEC9 (0.43) | CNR1HTR2CALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169038-A4 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-10-13 | — | — | EP | claimed |
| EP-1169038-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| WO-2000062778-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-10-26 | — | — | WO | claimed |