Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604450 | 0.93 | ROCK1 (0.54) | PARP1MCHR1MEN1KMT2APOLB | |
| SCHEMBL6602401 | 0.92 | MAPT (0.51) | PARP1MCHR1MEN1KMT2APOLB | |
| SCHEMBL6607020 | 0.90 | NR1H4 (0.62) | MCHR1MEN1KMT2APOLBNPC1 | |
| SCHEMBL6603223 | 0.89 | KMT2A (0.58) | PARP1MCHR1MEN1KMT2APOLB | |
| SCHEMBL6606889 | 0.87 | PARP1 (0.51) | PARP1MEN1KMT2APOLBNPC1 | |
| SCHEMBL6602805 | 0.85 | MCHR1 (0.62) | MCHR1MEN1KMT2APOLBHTR2C | |
| SCHEMBL6604027 | 0.83 | MAPT (0.58) | MCHR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6604459 | 0.80 | MAPT (0.52) | PARP1MEN1KMT2APOLBNPC1 | |
| SCHEMBL6602409 | 0.80 | MAPT (0.51) | PARP1MEN1KMT2APOLBNPC1 | |
| SCHEMBL6925375 | 0.80 | MCHR1 (0.78) | MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |