Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602654 | 0.94 | RAB9A (0.47) | CFTRKMT2AALDH1A1POLBPGR | |
| SCHEMBL6600453 | 0.93 | NPC1 (0.47) | CFTRKMT2AALDH1A1POLBPGR | |
| SCHEMBL6600681 | 0.92 | PDE4D (0.47) | CFTRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL6602109 | 0.91 | RAB9A (0.53) | CFTRKMT2AMAOBALDH1A1POLB | |
| SCHEMBL6603519 | 0.90 | MEN1 (0.45) | CFTRKMT2AALDH1A1POLBPGR | |
| SCHEMBL6601572 | 0.90 | NPC1 (0.56) | CFTRMAOBALDH1A1POLBPGR | |
| SCHEMBL6601859 | 0.89 | CFTR (0.50) | CFTRKMT2AMAOBALDH1A1POLB | |
| SCHEMBL147544 | 0.87 | LMNA (0.51) | KMT2AMAOBALDH1A1POLBABCG2 | |
| SCHEMBL6603307 | 0.87 | LMNA (0.54) | CFTRKMT2AMAOBALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7650133 | 0.86 | LMNA (0.50) | CFTRMAOBALDH1A1POLBABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922036-B1 | ARYLALKANOYL PYRIDAZINES | MERCK PATENT GMBH (DE) | 2004-03-24 | — | — | EP | disclosed |