Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607132 | 1.00 | MMP2 (0.32) | MMP2MMP13ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6758604 | 0.93 | — | — | |
| SCHEMBL6400568 | 0.87 | — | — | |
| SCHEMBL6608144 | 0.87 | — | — | |
| SCHEMBL6608153 | 0.87 | — | — | |
| SCHEMBL6401244 | 0.83 | — | — | |
| SCHEMBL6397626 | 0.78 | CHEK1 (0.35) | MMP2MMP13ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6397621 | 0.78 | CHEK1 (0.35) | MMP2MMP13ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6399472 | 0.77 | MASP2 (0.33) | — | |
| SCHEMBL6604993 | 0.77 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |