Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 6/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607401 | 0.92 | BDKRB1 (0.34) | BRS3BDKRB1 | |
| SCHEMBL6607743 | 0.90 | HTT (0.41) | AGTR1AGTR2BDKRB1 | |
| SCHEMBL6606968 | 0.86 | AGTR1 (0.47) | BRS3AGTR1AGTR2 | |
| SCHEMBL8944173 | 0.86 | KDM4E (0.40) | AGTR1AGTR2 | |
| SCHEMBL8548756 | 0.85 | AGTR1 (0.37) | BRS3AGTR1AGTR2 | |
| SCHEMBL6605990 | 0.84 | BRS3 (0.39) | BRS3AGTR1AGTR2BDKRB1 | |
| SCHEMBL8552543 | 0.81 | AGTR1 (0.38) | BRS3AGTR1AGTR2 | |
| SCHEMBL6610731 | 0.79 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL6605204 | 0.78 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL6607508 | 0.77 | AGTR1 (0.46) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829479-B1 | Heterocyclic compounds and their use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-0588299-B1 | 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0829479-A1 | Heterocyclic compounds and their use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |