Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605139 | 0.95 | TERT (0.33) | TERTCLK2CLK3DYRK1AATM | |
| SCHEMBL6599497 | 0.90 | SMPD3 (0.35) | TERTSMPD3KMT2A | |
| SCHEMBL4074857 | 0.90 | TERT (0.35) | TERT | |
| SCHEMBL6591832 | 0.89 | CLK2 (0.35) | TERTCLK2CLK3DYRK1AATM | |
| SCHEMBL6594969 | 0.87 | MEN1 (0.36) | TERTKMT2A | |
| SCHEMBL4082014 | 0.86 | ACVR1 (0.34) | TERT | |
| SCHEMBL4076584 | 0.86 | TERT (0.33) | TERT | |
| SCHEMBL6591886 | 0.86 | BRD4 (0.37) | — | |
| SCHEMBL6592153 | 0.85 | BMPR1B (0.38) | TERT | |
| SCHEMBL4076912 | 0.84 | TLR9 (0.37) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |