Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603565 | 0.74 | SLC6A2 (0.36) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6607186 | 0.69 | SLC6A3 (0.39) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3587511 | 0.67 | — | — | |
| SCHEMBL27929746 | 0.67 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10129328 | 0.67 | SLC6A3 (0.42) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL1515638 | 0.67 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL23062789 | 0.65 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL2331297 | 0.65 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL2325251 | 0.65 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL20357039 | 0.65 | SLC6A3 (0.36) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106614-B1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER (US) | 2004-01-07 | — | — | EP | disclosed |
| US-6444677-B2 | TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, ETC. | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| EP-1106614-A1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |