Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167320 | 0.89 | ACACB (0.38) | BDKRB1PRKCQPRKCD | |
| SCHEMBL6607208 | 0.82 | POLB (0.36) | BDKRB1PRKCQPRKCDPOLB | |
| SCHEMBL6610697 | 0.80 | POLB (0.39) | POLB | |
| SCHEMBL6612631 | 0.80 | SCN10A (0.42) | POLB | |
| SCHEMBL6608517 | 0.80 | SCN10A (0.40) | POLB | |
| SCHEMBL7046359 | 0.78 | KDM4E (0.44) | — | |
| SCHEMBL7455415 | 0.76 | RAF1 (0.36) | — | |
| SCHEMBL6166119 | 0.75 | AAK1 (0.38) | — | |
| SCHEMBL6167796 | 0.74 | ACACB (0.33) | BDKRB1PRKCQPRKCDPOLB | |
| SCHEMBL6435476 | 0.74 | KDR (0.36) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379511-A1 | DIHYDRO-BENZO (b) (1, 4) DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083652-A1 | DIHYDRO-BENZO [b] [1, 4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-24 | — | — | WO | disclosed |