Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL29023672 | 0.87 | ALDH1A1 (0.52) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL18079252 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL120873 | 0.80 | FDPS (0.46) | SMN1; SMN2TSHRGGPS1FDPS | |
| SCHEMBL592133 | 0.79 | — | — | |
| SCHEMBL30787208 | 0.78 | FDPS (0.48) | TSHRGGPS1FDPS | |
| SCHEMBL999089 | 0.78 | FDPS (0.48) | TSHRGGPS1FDPS | |
| SCHEMBL1092012 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL30787209 | 0.78 | FDPS (0.48) | TSHRGGPS1FDPS | |
| SCHEMBL258059 | 0.78 | FDPS (0.48) | TSHRGGPS1FDPS | |
| SCHEMBL30787223 | 0.78 | FDPS (0.48) | TSHRGGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480943-A2 | SYNTHESIS OF 3,5-DIHYDROXY-7-PYRROL-1-YL HEPTANOIC ACIDS | Teva Pharmaceutical Industries Limited (IL) | 2004-12-01 | — | — | EP | claimed |
| WO-2004046105-A2 | SYNTHESIS OF 3,5-DIHYDROXY-7-PYRROL-1-YL HEPTANOIC ACIDS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-06-03 | — | — | WO | claimed |