Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599951 | 0.83 | MEN1 (0.47) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL6600702 | 0.83 | MEN1 (0.56) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL12933385 | 0.82 | MEN1 (0.51) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL28628097 | 0.79 | MEN1 (0.56) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL18635352 | 0.79 | L3MBTL1 (0.40) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL30224786 | 0.78 | THRB (0.43) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL16705084 | 0.78 | CYP1A2 (0.46) | KMT2AHDAC1HDAC8HDAC6L3MBTL1 | |
| SCHEMBL23993199 | 0.78 | THRB (0.43) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL17962772 | 0.77 | THRB (0.46) | L3MBTL1BACE1CYP1A2SMN1; SMN2 | |
| SCHEMBL9663555 | 0.76 | MAPT (0.61) | MEN1MAPTKMT2AHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |
| CN-109400594-A | Metal enzyme inhibitor compound | 威尔金制药(NC)有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-103930418-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-07-16 | — | — | CN | disclosed |
| CN-103857675-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-06-11 | — | — | CN | disclosed |
| US-8697739-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2014-04-15 | — | — | US | disclosed |
| EP-1009748-A1 | 3-ALKYLPYRROLO 3,2-$i(c)]QUINOLINE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000001696-A1 | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-13 | — | — | WO | disclosed |
| EP-0968208-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS USEFUL IN THERAPY, PARTICULARLY IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | Pfizer Limited (GB) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998030560-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS USEFUL IN THERAPY, PARTICULARLY IN THE TREATMENT OF BEGNIN PROSTATIC HYPERPLASIA | PFIZER LIMITED (GB) | 1998-07-16 | — | — | WO | disclosed |