Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836252 | 0.96 | IDH2 (0.50) | IDH2EHMT2EHMT1ADORA3RAB9A | |
| SCHEMBL4832352 | 0.93 | IDH2 (0.53) | IDH2EHMT2EHMT1ADORA3IRAK4 | |
| SCHEMBL5420312 | 0.85 | IDH2 (0.48) | IDH2EHMT2EHMT1RAB9AIRAK4 | |
| SCHEMBL14268864 | 0.82 | IDH2 (0.48) | IDH2EHMT2EHMT1RAB9AIRAK4 | |
| SCHEMBL5038228 | 0.82 | BCL6 (0.56) | IDH2EHMT2EHMT1RAB9A | |
| SCHEMBL6856715 | 0.82 | EHMT2 (0.54) | IDH2EHMT2EHMT1CTSLCTSS | |
| SCHEMBL5029195 | 0.82 | IDH2 (0.57) | IDH2EHMT2EHMT1CTSLCTSS | |
| SCHEMBL14274165 | 0.81 | CTSL (0.59) | IDH2EHMT2EHMT1RAB9ACTSL | |
| SCHEMBL6016997 | 0.81 | IDH2 (0.43) | IDH2EHMT2ADORA3RAB9AJAK3 | |
| SCHEMBL4879100 | 0.81 | RAB9A (0.47) | IDH2EHMT2EHMT1RAB9AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436266-A4 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1436266-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024926-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2003-03-27 | — | — | WO | claimed |
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | disclosed |