Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360910 | 0.91 | PPARA (0.47) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL27388283 | 0.91 | PPARA (0.48) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL27529292 | 0.90 | PPARA (0.49) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6605626 | 0.90 | PPARA (0.56) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL14379043 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL20125593 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL29358494 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL3922 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL27407252 | 0.82 | PPARA (0.41) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL27387596 | 0.82 | PPARA (0.41) | PPARAPPARGPPARDPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881219-B1 | N-SUBSTITUTED DIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-04-07 | — | — | EP | claimed |
| CN-1065863-C | N-substituted dioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 2001-05-16 | — | — | CN | claimed |
| US-5948803-A | IMPROVE THE INSULIN RESISTANCE AND HAVE POTENT HYPOGLYCEMIC EFFECT AND LIPID-LOWERING EFFECT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-09-07 | — | — | US | claimed |
| CN-1205695-A | N-substituted dioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 1999-01-20 | — | — | CN | claimed |
| EP-0881219-A1 | N-SUBSTITUTED DIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | claimed |
| EP-0881219-B1 | N-SUBSTITUTED DIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-04-07 | — | — | EP | disclosed |
| CN-1065863-C | N-substituted dioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 2001-05-16 | — | — | CN | disclosed |
| US-5948803-A | IMPROVE THE INSULIN RESISTANCE AND HAVE POTENT HYPOGLYCEMIC EFFECT AND LIPID-LOWERING EFFECT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| CN-1205695-A | N-substituted dioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 1999-01-20 | — | — | CN | disclosed |
| EP-0881219-A1 | N-SUBSTITUTED DIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |