Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599751 | 1.00 | PGD (0.40) | PGDSLC22A6FFAR3GPR84SMN1; SMN2 | |
| SCHEMBL6607495 | 1.00 | PGD (0.40) | PGDSLC22A6FFAR3GPR84SMN1; SMN2 | |
| SCHEMBL6599755 | 1.00 | PGD (0.40) | PGDSLC22A6FFAR3GPR84SMN1; SMN2 | |
| SCHEMBL4807998 | 0.78 | PGD (0.43) | PGDSLC22A6FFAR3GPR84SMN1; SMN2 | |
| SCHEMBL4806982 | 0.78 | PGD (0.43) | PGDSLC22A6FFAR3GPR84SMN1; SMN2 | |
| SCHEMBL3650683 | 0.74 | PGD (0.47) | PGDSLC22A6GPR84SMN1; SMN2MAPT | |
| SCHEMBL6599512 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL7816466 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL6599515 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL6599508 | 0.72 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080082-B1 | INTERMEDIATES FOR THE SYNTHESIS OF EPOTHILONES AND METHODS FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2004-10-06 | — | — | EP | disclosed |