Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 15/20 | 0.46 |
| ▸ | CALML3 | P27482 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606974 | 0.90 | MAOA (0.46) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL6607943 | 0.87 | MAOA (0.49) | MAOACALML3MAOB | |
| SCHEMBL6609507 | 0.86 | MAOA (0.47) | MAOACALML3 | |
| SCHEMBL6609145 | 0.86 | CALML3 (0.49) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL6607909 | 0.86 | CALML3 (0.49) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL6609246 | 0.85 | MAOA (0.46) | MAOACALML3 | |
| SCHEMBL6607503 | 0.85 | CALML3 (0.47) | MAOACALML3CYP3A4CYP2D6 | |
| SCHEMBL6609091 | 0.85 | CYP3A4 (0.49) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL7082522 | 0.85 | MAOA (0.45) | MAOACALML3MAOB | |
| SCHEMBL6607500 | 0.85 | CALML3 (0.54) | MAOACALML3CYP3A4CYP2D6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082322-B1 | OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-01-28 | — | — | EP | claimed |
| EP-1082322-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | claimed |
| WO-1999064416-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | claimed |
| EP-1082322-B1 | OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1357122-A2 | Oxazolidinone compounds and pharmaceutical compositions containing them | AstraZeneca AB (SE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1082322-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064416-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |