Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 15/20 | 0.47 |
| ▸ | CALML3 | P27482 | 4/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606974 | 0.88 | MAOA (0.46) | MAOACALML3GRM2 | |
| SCHEMBL6607708 | 0.86 | MAOA (0.46) | MAOACALML3 | |
| SCHEMBL7077703 | 0.86 | MAOA (0.46) | MAOACALML3 | |
| SCHEMBL6609246 | 0.86 | MAOA (0.46) | MAOACALML3GRM2 | |
| SCHEMBL6607503 | 0.85 | CALML3 (0.47) | MAOACALML3 | |
| SCHEMBL7082522 | 0.84 | MAOA (0.45) | MAOACALML3 | |
| SCHEMBL7077035 | 0.84 | MAOA (0.44) | MAOACALML3 | |
| SCHEMBL6609145 | 0.84 | CALML3 (0.49) | MAOACALML3 | |
| SCHEMBL6607909 | 0.84 | CALML3 (0.49) | MAOACALML3 | |
| SCHEMBL6607485 | 0.83 | MAOA (0.45) | MAOACALML3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082322-B1 | OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1357122-A2 | Oxazolidinone compounds and pharmaceutical compositions containing them | AstraZeneca AB (SE) | 2003-10-29 | — | — | EP | disclosed |