Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608441 | 0.74 | MAPT (0.70) | MAPTALDH1A1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6610702 | 0.73 | MAPT (0.72) | MAPTALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL7976500 | 0.70 | ALDH1A1 (0.54) | MAPTALDH1A1PDCD1CD274HTR2A | |
| SCHEMBL6607314 | 0.69 | MAPT (0.56) | MAPTHTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL7976524 | 0.69 | ALDH1A1 (0.56) | MAPTALDH1A1PDCD1CD274HTR2A | |
| SCHEMBL6607643 | 0.68 | MAPT (0.49) | MAPTPDCD1CD274HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6610212 | 0.68 | MAPT (0.58) | MAPTHTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL11839438 | 0.67 | MAPT (0.60) | MAPTALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL19000315 | 0.67 | ALDH1A1 (0.55) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL6611810 | 0.66 | MAPT (0.97) | MAPTALDH1A1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997462-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | NIPPON KAYAKU KK (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6294547-B1 | Naphthyridine deratives or salts thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |