Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601742 | 0.88 | ALDH1A1 (0.36) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6597050 | 0.87 | RAB9A (0.37) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6596825 | 0.83 | CYP26A1 (0.45) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6599372 | 0.81 | — | — | |
| SCHEMBL6598966 | 0.80 | ALDH1A1 (0.43) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6601595 | 0.79 | CYP26A1 (0.39) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8310276 | 0.78 | CHRM2 (0.41) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5800338 | 0.78 | CYP26A1 (0.37) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8314615 | 0.77 | MAPT (0.33) | MAPTNPC1RAB9AHBBALDH1A1 | |
| SCHEMBL8314939 | 0.77 | MAOB (0.34) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |