Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30862344 | 1.00 | MMP8 (0.51) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL14130590 | 0.86 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL606117 | 0.86 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL23342965 | 0.86 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL11938487 | 0.86 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL8926506 | 0.84 | MMP8 (0.53) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL9126861 | 0.82 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL31556283 | 0.82 | KMT2A (0.58) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL8776709 | 0.82 | ALOX15 (0.49) | MEN1NPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8776680 | 0.82 | ALOX15 (0.49) | MEN1NPC1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568701-B1 | TRANSITION METAL COMPLEX HAVING DIPHOSPHINE COMPLEX AS LIGAND | TAKEDA PHARMACEUTICAL (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1114815-B1 | Process to prepare taxol | UPJOHN CO (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1352900-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-1352899-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0912504-B1 | Oxazolidine ester | UPJOHN CO (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6307064-B1 | PHENYLISOSERINE ESTER OF SILYLATED BACCATIN III | PHARMACIA & UPJOHN COMPANY | 2001-10-23 | — | — | US | disclosed |
| EP-1114815-A2 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6177573-B1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2001-01-23 | — | — | US | disclosed |
| US-6057452-A | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2000-05-02 | — | — | US | disclosed |
| EP-0912504-A1 | PROCESS TO PREPARE TAXOL | PHARMACIA & UPJOHN COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| CN-1216039-A | Process for preparing taxol | UPJOHN CO (US) | 1999-05-05 | — | — | CN | disclosed |
| WO-1997042167-A1 | PROCESS TO PREPARE TAXOL | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |