Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 11/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607109 | 0.86 | RECQL (0.44) | PDGFRBPDGFRARECQLPDE4APDE4B | |
| SCHEMBL6606929 | 0.82 | PDGFRB (0.39) | PDGFRBPDGFRARECQLPDE4APDE4B | |
| SCHEMBL10948586 | 0.80 | NPC1 (0.41) | — | |
| SCHEMBL7356246 | 0.75 | PDE4D (0.46) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5309679 | 0.75 | PDE4B (0.56) | RECQLPDE4APDE4BPDE4DPDE4C | |
| SCHEMBL14244189 | 0.75 | RECQL (0.60) | PDGFRBPDGFRARECQLPDE4APDE4B | |
| SCHEMBL72986 | 0.73 | KMT2A (0.54) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6606739 | 0.72 | PDE4A (0.46) | PDGFRBPDGFRAPDE4APDE4BPDE4D | |
| SCHEMBL71189 | 0.72 | PDE4D (0.46) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL24851926 | 0.72 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169792-C | Substituted vinylpyridine derivatives and medicaments containing them | ������ҩ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| CN-1206407-A | Substituted vinylpyridine derivatives and medicaments containing them | SS PHARMACEUTICAL CO (JP) | 1999-01-27 | — | — | CN | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |