Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298897 | 1.00 | TSHR (0.42) | TSHRTP53MAOBCALM1TDP1 | |
| SCHEMBL5573317 | 0.79 | MAOB (0.43) | TSHRTP53MAOBCALM1TDP1 | |
| SCHEMBL4340623 | 0.76 | TP53 (0.39) | TSHRTP53MAOBCALM1TDP1 | |
| SCHEMBL2241623 | 0.73 | MAOB (0.50) | TSHRTP53MAOBCALM1ALDH1A1 | |
| SCHEMBL9853133 | 0.73 | MAOB (0.40) | TSHRTP53MAOBCALM1ALDH1A1 | |
| SCHEMBL1195145 | 0.73 | MAOB (0.40) | TSHRTP53MAOBCALM1ALDH1A1 | |
| SCHEMBL2241624 | 0.73 | MAOB (0.50) | TSHRTP53MAOBCALM1ALDH1A1 | |
| SCHEMBL8396961 | 0.73 | TP53 (0.41) | TP53MAOBCALM1IDO1 | |
| SCHEMBL18245119 | 0.71 | KCNH2 (0.40) | TSHRTP53MAOBCALM1TDP1 | |
| SCHEMBL97491 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | claimed |
| EP-1161222-A1 | METHOD OF TREATING HAIR LOSS USING NON-IMMUNOSUPPRESSIVE COMPOUNDS | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000051558-A1 | METHOD OF TREATING HAIR LOSS USING NON-IMMUNOSUPPRESSIVE COMPOUNDS | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2000-09-08 | — | — | WO | claimed |
| CN-105593234-B | Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product | 道康宁东丽株式会社 | 2018-10-26 | — | — | CN | disclosed |
| CN-105593234-A | Novel organopolysiloxane, surface treatment agent comprising the same, resin composition comprising the same, and gelatinous product or cured product thereof | DOW CORNING TORAY CO LTD | 2016-05-18 | — | — | CN | disclosed |
| EP-1484328-A1 | Derivatives of quinolyl-propyl-piperidine and their use as antimicrobial agents | Aventis Pharma S.A. (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |