Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770452 | 0.92 | RPS6KB1 (0.51) | SYKMAPK1HTTRPS6KB1JAK3 | |
| SCHEMBL6770161 | 0.91 | SYK (0.47) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL6777397 | 0.90 | SYK (0.46) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL6769860 | 0.87 | SYK (0.52) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL6766170 | 0.86 | KDR (0.46) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL761284 | 0.85 | SYK (0.54) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL6610211 | 0.85 | SYK (0.55) | SYKPDGFRBPDGFRAMAPK1RPS6KB1 | |
| SCHEMBL6769391 | 0.84 | PDGFRB (0.66) | SYKPDGFRBPDGFRAEGFRFGFR1 | |
| SCHEMBL7081409 | 0.84 | SYK (0.46) | SYKPDGFRBPDGFRAMAPK1HTT | |
| SCHEMBL6772485 | 0.84 | HSD17B10 (0.46) | PDGFRBPDGFRALMNAEGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235806-A4 | NOVEL 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | DONG WHA PHARM IND CO LTD (KR) | 2004-02-04 | — | — | EP | disclosed |
| EP-1235806-A1 | NOVEL 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038308-A1 | NOVEL 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD (KR) | 2001-05-31 | — | — | WO | disclosed |