Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.45 |
| ▸ | CLK2 | P49760 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | PAK4 | O96013 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.45 |
| ▸ | STK3 | Q13188 | 2/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769085 | 0.92 | SYK (0.52) | SYKKDRMAPK1HTTNPC1 | |
| SCHEMBL761284 | 0.89 | SYK (0.54) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL761282 | 0.88 | SYK (0.66) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL20354302 | 0.87 | SYK (0.52) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6608523 | 0.87 | SYK (0.48) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6610211 | 0.87 | SYK (0.55) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6766065 | 0.86 | SYK (0.51) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6770161 | 0.85 | SYK (0.47) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6777397 | 0.85 | SYK (0.46) | SYKKDRMAP4K4CLK2DYRK1A | |
| SCHEMBL6766487 | 0.84 | SYK (0.47) | SYKKDRMAP4K4CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762189-B1 | HEPATITIS B VIRUS AND HUMAN IMMUNODEFICIENCY VIRUS ANTIPROLIFERATION AGENTS; REDUCED CHANCE OF TOXICITY, SIDE EFFECTS, AND DEVELOPMENT OF RESISTANT VIRAL STRAINS | DONG WHA PHARM. IND. CO., LTD. (KR) | 2004-07-13 | — | — | US | disclosed |