Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448818 | 0.96 | LTA4H (0.75) | LTA4HCHEK2 | |
| SCHEMBL11447699 | 0.95 | LTA4H (0.61) | LTA4H | |
| Hydrochloric Acid SCHEMBL7494733 | 0.94 | LTA4H (0.73) | LTA4HCHEK2 | |
| SCHEMBL7443334 | 0.93 | LTA4H (0.60) | LTA4HCHEK2 | |
| Hydrochloric Acid SCHEMBL7494004 | 0.92 | LTA4H (0.59) | LTA4H | |
| SCHEMBL7445359 | 0.90 | LTA4H (0.56) | LTA4HCHEK2 | |
| SCHEMBL7445314 | 0.90 | LTA4H (0.56) | LTA4HCHEK2 | |
| Hydrochloric Acid SCHEMBL7435059 | 0.89 | LTA4H (0.55) | LTA4HCHEK2 | |
| SCHEMBL6600614 | 0.85 | NFE2L2 (0.60) | LTA4HCHEK2 | |
| SCHEMBL11447913 | 0.85 | LTA4H (0.50) | LTA4HCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435955-A2 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SmithKline Beecham P.L.C. (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2002089800-A2 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-11-14 | — | — | WO | disclosed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |