Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 8/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611486 | 0.91 | ALOX15 (0.48) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6609890 | 0.90 | ALOX15 (0.48) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6615517 | 0.90 | ALOX15 (0.47) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6614279 | 0.88 | ALOX15 (0.51) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6609500 | 0.88 | ALOX15 (0.50) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL5841837 | 0.85 | ALOX15 (0.57) | ALOX15MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6609870 | 0.84 | ALOX15 (0.55) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6612330 | 0.84 | MAPT (0.38) | BCHEMAOBACHECHRNA7ALDH1A1 | |
| SCHEMBL6614053 | 0.82 | ALOX15 (0.41) | ALOX15BCHEMAOBACHEMEN1 | |
| SCHEMBL6610127 | 0.82 | MAPT (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |