Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609890 | 0.92 | ALOX15 (0.48) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6609210 | 0.91 | ALOX15 (0.47) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6615517 | 0.91 | ALOX15 (0.47) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6614279 | 0.90 | ALOX15 (0.51) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6609500 | 0.89 | ALOX15 (0.50) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6614053 | 0.89 | ALOX15 (0.41) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL6609870 | 0.86 | ALOX15 (0.55) | ALOX15BCHEMAOBMEN1KMT2A | |
| SCHEMBL5841574 | 0.84 | ALOX15 (0.59) | ALOX15MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6611013 | 0.83 | MAPT (0.39) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL6612072 | 0.81 | MTNR1A (0.40) | MEN1KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | claimed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | claimed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |