Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741235 | 0.81 | HTR2C (0.45) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL11558603 | 0.79 | SLC6A4 (0.59) | SLC6A4SLC6A2HTR1ASLC6A3HTR2C | |
| SCHEMBL6606771 | 0.77 | SLC6A2 (0.40) | SLC6A4SLC6A2HTR1ASSTR4SSTR1 | |
| SCHEMBL1638122 | 0.76 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL28776903 | 0.76 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL25355557 | 0.76 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL5566775 | 0.76 | HTR2C (0.54) | SLC6A4SLC6A2HTR1ASLC6A3HTR2C | |
| SCHEMBL28205555 | 0.75 | KMT2A (0.40) | SLC6A4SLC6A2HTR1ASLC6A3SSTR4 | |
| SCHEMBL13999230 | 0.75 | SLC6A2 (0.62) | SLC6A4SLC6A2HTR1ASLC6A3HTR2C | |
| SCHEMBL25355022 | 0.72 | HTR2A (0.48) | SLC6A4SLC6A2HTR1ASLC6A3SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | disclosed |