Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 8/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609212 | 0.77 | SLC6A4 (0.39) | SLC6A2SLC6A4DRD2ADRA1DADRA1A | |
| SCHEMBL13999230 | 0.70 | SLC6A2 (0.62) | SLC6A2SLC6A4HTR2CHTR1A | |
| SCHEMBL8581317 | 0.68 | GRIN2B (0.37) | SLC6A2SLC6A4DRD2ADRA1DADRA1A | |
| SCHEMBL28288419 | 0.66 | MAPT (0.52) | SLC6A2SLC6A4 | |
| SCHEMBL5473619 | 0.64 | SLC6A2 (0.62) | SLC6A2SLC6A4DRD2ADRA1DADRA1A | |
| SCHEMBL31449823 | 0.63 | GSK3B (0.39) | GSK3B | |
| Hydrochloric Acid SCHEMBL5858161 | 0.63 | HTR1A (0.61) | SLC6A2SLC6A4DRD2ADRA1DADRA1A | |
| SCHEMBL5097593 | 0.62 | DRD2 (0.56) | DRD2ADRA1DADRA1AADRA1BSSTR1 | |
| SCHEMBL16640390 | 0.62 | SLC6A9 (0.50) | GSK3BPDE10A | |
| SCHEMBL31235614 | 0.61 | KDM4E (0.50) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | disclosed |