Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLTP | P55058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212166 | 0.91 | PTGDR2 (0.54) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6608445 | 0.91 | PLTP (0.47) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5210754 | 0.90 | MAPT (0.44) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5207488 | 0.88 | MAPT (0.40) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5212864 | 0.87 | PTGDR2 (0.43) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5214026 | 0.87 | ALDH1A1 (0.41) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5212184 | 0.86 | MAPT (0.59) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6611692 | 0.86 | MAPT (0.38) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5210337 | 0.86 | PTGDR2 (0.42) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5214955 | 0.86 | PTGDR2 (0.46) | PTGDR2MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |