Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570052 | 0.94 | GSK3B (0.57) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5660844 | 0.94 | GSK3B (0.61) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5662338 | 0.92 | GSK3B (0.59) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5660040 | 0.92 | GSK3B (0.59) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6609685 | 0.89 | MMP1 (0.63) | GSK3BNPC1KMT2AMEN1MAPT | |
| SCHEMBL9712507 | 0.87 | GSK3B (0.68) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL653535 | 0.87 | GSK3B (0.68) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6610011 | 0.84 | MMP1 (0.61) | GSK3BNPC1KMT2AMEN1MAPT | |
| SCHEMBL16552727 | 0.84 | GSK3B (0.70) | GSK3BNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL862889 | 0.83 | NPC1 (0.76) | NPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335374-B | GLP-1R modulating compounds | 吉利德科学公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20250099431-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2025-03-27 | — | — | US | disclosed |
| EP-4523751-A2 | GLP-1R MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4097097-B1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-01-15 | — | — | EP | disclosed |
| US-12121511-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| CN-115335374-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-11-11 | — | — | CN | disclosed |
| US-20220288030-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-09-15 | — | — | US | disclosed |
| US-20220288030-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-09-15 | — | — | US | disclosed |
| EP-3683222-B1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021154796-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| US-4921528-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4870088-A | ANIMALS AND PLANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0237917-A2 | 1,1-Disubstituted cyclopropane derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0180850-A2 | Antimycotic azolyl-methyl-cyclopropyl-carbinol derivatives | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180136-A2 | Substituted azolylmethyl-cyclopropyl carbinol derivatives | BAYER AG (DE) | 1986-05-07 | — | — | EP | disclosed |
| US-4515793-A | PARASITICIDES | EDNA MCCONNELL CLARK FOUNDATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| US-4358457-A | ANTICONVULSANTS, ANALGESICS, AND MUSCLE RELAXANTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4045568-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-3979444-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, HYPOTENSIVES | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12121511-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | GSK3B 485/4885NPC1 1254/4885RAB9A 460/4885 |
| US-20250099431-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | GSK3B 485/4885NPC1 1254/4885RAB9A 460/4885 |
| US-20220288030-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | GSK3B 485/4885NPC1 1254/4885RAB9A 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.