Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | WNT3 | P56703 | 2/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832241 | 0.97 | F10 (0.56) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL3830280 | 0.88 | F10 (0.59) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL6598342 | 0.82 | F10 (0.53) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL7084714 | 0.81 | F10 (0.80) | F10NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7083057 | 0.81 | F10 (0.80) | F10NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL3833613 | 0.81 | NPSR1 (0.54) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL3833239 | 0.81 | GPR119 (0.51) | LMNANPSR1MEN1KMT2AGPR119 | |
| SCHEMBL3833308 | 0.79 | NPSR1 (0.59) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL3830720 | 0.79 | LMNA (0.52) | F10LMNANPSR1MEN1KMT2A | |
| SCHEMBL3834148 | 0.78 | NPSR1 (0.54) | F10LMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | disclosed |