Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609730 | 1.00 | MAOB (0.39) | MAOBHPGDMAPK1SMN1; SMN2HRH2 | |
| SCHEMBL6610157 | 0.91 | MAPT (0.38) | MAOBHPGDMAPK1SMN1; SMN2HRH2 | |
| SCHEMBL6610154 | 0.91 | MAPT (0.38) | MAOBHPGDMAPK1SMN1; SMN2HRH2 | |
| SCHEMBL6609674 | 0.89 | MAOB (0.40) | MAOBMAPK1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6609669 | 0.89 | MAOB (0.40) | MAOBMAPK1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6616648 | 0.88 | MAOB (0.39) | MAOBHPGDMAPK1SMN1; SMN2HRH2 | |
| SCHEMBL6616653 | 0.88 | MAOB (0.39) | MAOBHPGDMAPK1SMN1; SMN2HRH2 | |
| SCHEMBL27572351 | 0.81 | LTA4H (0.39) | MAOBSMN1; SMN2LTA4HPTGS1PTGS2 | |
| SCHEMBL7568322 | 0.80 | HTR7 (0.45) | MAOBSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7568325 | 0.80 | HTR7 (0.45) | MAOBSMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |