Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 0.35 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604500 | 0.90 | PDE4D (0.37) | PDE4DPDE4APDE4BPDE4CPLAU | |
| SCHEMBL6604220 | 0.78 | KDM4E (0.41) | PDE4DPDE4APDE4BPDE4CF9 | |
| SCHEMBL6608204 | 0.75 | ALDH1A1 (0.36) | PDE4DKDM4EALDH1A1MAPTBRD4 | |
| SCHEMBL6604464 | 0.74 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CMAPT | |
| SCHEMBL6606725 | 0.71 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4CPLAU | |
| SCHEMBL6611886 | 0.70 | HTT (0.36) | ALDH1A1PIK3CGMAPTBRD4KCNK3 | |
| SCHEMBL6612329 | 0.69 | KDM4E (0.35) | F9F10PLAUKDM4EALDH1A1 | |
| SCHEMBL6610234 | 0.68 | MAPT (0.32) | F9F10PLAUKDM4EALDH1A1 | |
| SCHEMBL6607492 | 0.67 | PDE4A (0.42) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| SCHEMBL7019078 | 0.67 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CF9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257548-B1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2004-05-06 | — | — | EP | claimed |