Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609411 | 0.95 | GAA (0.49) | GAAAOC3MAOAMAOBFNTA | |
| SCHEMBL3196016 | 0.84 | GAA (0.51) | GAAAOC3MAOAMAOBFNTA | |
| SCHEMBL30949073 | 0.84 | AOC3 (0.48) | GAAAOC3LMNASMN1; SMN2DRD2 | |
| SCHEMBL30949064 | 0.84 | AOC3 (0.48) | GAAAOC3LMNASMN1; SMN2DRD2 | |
| SCHEMBL6611215 | 0.83 | MAOA (0.40) | GAAMAOAMAOBFNTAFNTB | |
| SCHEMBL28748062 | 0.79 | AOC3 (0.44) | GAAAOC3LMNASMN1; SMN2UTS2R | |
| SCHEMBL6614153 | 0.78 | MAOA (0.41) | GAAMAOAMAOBFNTAFNTB | |
| SCHEMBL3917591 | 0.78 | AOC3 (0.50) | GAAAOC3LMNASMN1; SMN2DRD2 | |
| SCHEMBL3917589 | 0.78 | AOC3 (0.50) | GAAAOC3LMNASMN1; SMN2DRD2 | |
| SCHEMBL9607479 | 0.77 | LMNA (0.48) | GAAAOC3MAOAMAOBFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |