Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391830 | 0.87 | FDPS (0.52) | FDPSSMPD1TSHRGGPS1 | |
| SCHEMBL999922 | 0.87 | FDPS (0.48) | FDPSSMPD1GGPS1 | |
| SCHEMBL1271337 | 0.87 | FDPS (0.52) | FDPSSMPD1TSHRGGPS1 | |
| SCHEMBL7011302 | 0.85 | FDPS (0.46) | FDPSSMPD1GGPS1 | |
| SCHEMBL27323412 | 0.84 | DNM1 (0.52) | FDPSSMPD1DNM1MEN1KMT2A | |
| SCHEMBL7719887 | 0.83 | FDPS (0.48) | FDPSSMPD1GGPS1 | |
| SCHEMBL14966859 | 0.82 | — | — | |
| SCHEMBL14840328 | 0.82 | FDPS (0.48) | FDPSSMPD1ALDH1A1TSHRGGPS1 | |
| SCHEMBL3032913 | 0.81 | SMN1; SMN2 (0.43) | FDPSSMPD1MEN1KMT2AALDH1A1 | |
| SCHEMBL4631586 | 0.81 | SMN1; SMN2 (0.57) | FDPSSMPD1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389202-B1 | 2,6-SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORP (US) | 2004-09-29 | — | — | EP | disclosed |