SCHEMBL661008

SCHEMBL661008

NC1Cc2ccccc2C1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
SIGMAR1 Q99720 2/20 0.42
KDM1A O60341 4/20 0.42
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HTR2A P28223 1/20 0.39
ANPEP P15144 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4652712 0.91 ALDH1A1 (0.41) ALDH1A1GAAMAPTSIGMAR1KDM1A
SCHEMBL562899 0.85 KDM1A (0.42) ALDH1A1GAASIGMAR1KDM1AHTR2A
SCHEMBL1812009 0.82 TSHR (0.45) TSHRNPSR1ANPEP
SCHEMBL24650850 0.80 CYP3A4 (0.38) ALDH1A1KDM1ATSHR
SCHEMBL7891735 0.79 MEN1 (0.44) ALDH1A1GAAMAPTTSHRNPSR1
SCHEMBL7891742 0.79 MEN1 (0.44) ALDH1A1GAAMAPTTSHRNPSR1
SCHEMBL8045772 0.79 ALDH1A1 (0.41) ALDH1A1GAAMAPTTSHRNPSR1
SCHEMBL3327022 0.79 ALDH1A1 (0.41) ALDH1A1GAAMAPTTSHRNPSR1
SCHEMBL8410178 0.79 ALDH1A1 (0.41) ALDH1A1GAAMAPTTSHRNPSR1
SCHEMBL7891740 0.79 MEN1 (0.44) ALDH1A1GAAMAPTTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022238507-A1 THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS AWAKN LS EUROPE HOLDINGS LIMITED (IE) 2022-11-17 WO disclosed
WO-2014202993-A1 BINDING MOTIF FOR THROMBIN INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2014-12-24 WO disclosed
CN-101108878-B Glp-1 analogues SOD CONSEILS RECH APPLIC 2012-08-29 CN disclosed
CN-1935839-B Analogues of GLP-1 IPSEN PHARMA SAS (FR) 2012-06-06 CN disclosed
US-20120045393-A1 LHRH-II PEPTIDE ANALOGS BRACCO IMAGING SPA (IT) 2012-02-23 US disclosed
WO-2009144432-A1 MC4-R AGONISTS FOR THE TREATMENT OF OBESITY PALATIN TECHNOLOGIES, INC. (US) 2009-12-03 WO disclosed
CN-100540566-C Glucagon-like peptide-1 analogs SOD CONSEILS RECH APPLIC (FR) 2009-09-16 CN disclosed
US-7550602-B1 Small molecule compositions for sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-06-23 US disclosed
US-7456184-B2 Melanocortin receptor-specific compounds PALATIN TECHNOLOGIES INC. (US) 2008-11-25 US disclosed
EP-1622618-A4 MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS PALATIN TECHNOLOGIES INC (US) 2008-08-27 EP disclosed
CN-1342166-A Glucagon-like peptide-1 analogs SOD CONSEILS RECH APPLIC (FR) 2002-03-27 CN disclosed
CN-1329620-A Glucagon-like peptide-1 analogs CONSEILS DE RECH SET D APPLIC (FR) 2002-01-02 CN disclosed
EP-0649434-B1 RADIOACTIVELY-LABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATIDE INC (US) 2001-08-01 EP disclosed
EP-1094074-A2 Radioactively-labeled somatostatin derived peptides for imaging and therapeutic uses Diatide, Inc. (US) 2001-04-25 EP disclosed
US-6207643-B1 PSEUDOPEPTIDE ANALOGS ARE PRODUCED WHICH EXHIBIT AN OVERALL AMPHIPHILIC NATURE AND WHICH ARE CAPABLE OF PENETRATING THE INSECT CUTICLE WHILE STILL RETAINING BIOLOGICAL ACTIVITY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2001-03-27 US disclosed
WO-2000029010-A1 MIMETIC INSECT ALLATOSTATIN ANALOGS FOR INSECT CONTROL THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2000-05-25 WO disclosed
CN-1232038-A New peptide compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-10-20 CN disclosed
US-5871711-A MEDICAL DIAGNOSIS LABELED WITH TECHNETIUM FOR PEPTIDES DIATIDE, INC. (US) 1999-02-16 US disclosed
EP-0649434-A1 RADIOACTIVELY-LABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES Diatide, Inc. (US) 1995-04-26 EP disclosed
WO-1994000489-A2 RADIOACTIVELY-LABELED SOMATOSTANTIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1994-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045393-A1 LHRH-II PEPTIDE ANALOGS LHCGR, GNRHR, FSHR ALDH1A1 4273/4885GAA 1399/4885MAPT 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.