Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842692 | 0.75 | NOTUM (0.42) | KDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28831331 | 0.72 | NOTUM (0.40) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1498069 | 0.72 | NOTUM (0.40) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL599331 | 0.72 | LDHA (0.44) | ALDH1A1CYP1A2 | |
| SCHEMBL6610449 | 0.71 | KDM4E (0.34) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1060726 | 0.70 | NOTUM (0.39) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6916335 | 0.70 | LDHA (0.43) | ALDH1A1CYP1A2 | |
| SCHEMBL1234975 | 0.70 | LDHA (0.43) | ALDH1A1CYP1A2 | |
| SCHEMBL6918114 | 0.70 | LDHA (0.43) | ALDH1A1CYP1A2 | |
| SCHEMBL6916630 | 0.70 | LDHA (0.43) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | disclosed |
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | DDT, CYP2E1, CYP1A1 | HTT 2450/4885KDM4E 1089/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.