SCHEMBL1234975

SCHEMBL1234975

Cc1c(C)c(C(=O)O)c(C)c(C(=O)O)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.43
LDHB P07195 2/20 0.43
NOTUM Q6P988 1/20 0.39
CYP3A4 P08684 1/20 0.37
ACHE P22303 1/20 0.37
CYP1A2 P05177 1/20 0.36
PDE10A Q9Y233 2/20 0.35
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
TPMT P51580 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599331 0.97 LDHA (0.44) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6917144 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL30602301 0.93 NOTUM (0.39) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6909442 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6916838 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6916335 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL1060726 0.93 NOTUM (0.39) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6916630 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6918114 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE
SCHEMBL6913538 0.93 LDHA (0.43) LDHALDHBNOTUMCYP3A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167995-B Plasticized PVC compounds having surface-modified macromolecules and articles made therefrom 界面生物公司 2022-07-01 CN disclosed
CN-106905802-B Antifouling coating composition and coated article having coating film thereof 关西涂料株式会社 2021-06-25 CN disclosed
EP-2527399-B1 POLYESTER RESIN COMPOSITION FUJIFILM CORP (JP) 2016-06-01 EP disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-7884146-B2 acrylic acid-based polymers, polyesters, and polycarbonates, and resistant to precipitation of benzodithiole compound or bleeding out during long-term use, superior in long-wavelength ultraviolet absorption capacity, improved lightfastness FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-20100105814-A1 ULTRAVIOLET ABSORBENT AND POLYMER MATERIAL CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-20100076124-A1 POLYMER MATERIAL CONTAINING ULTRAVIOLET ABSORBENT FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100010123-A1 ULTRAVIOLET ABSORBENT AND POLYMER MATERIAL CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-01-14 US disclosed
EP-0102913-A2 Polyterephthalates having high clarity and process for making same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076124-A1 POLYMER MATERIAL CONTAINING ULTRAVIOLET ABSORBENT F12, MRPS22, PWWP2B LDHA 3080/4885LDHB 2744/4885NOTUM 3818/4885
US-20100105814-A1 ULTRAVIOLET ABSORBENT AND POLYMER MATERIAL CONTAINING THE SAME UGT1A6, MCM6, MSH6 LDHA 3774/4885LDHB 3939/4885NOTUM 3910/4885
US-20100010123-A1 ULTRAVIOLET ABSORBENT AND POLYMER MATERIAL CONTAINING THE SAME SSR4, MCM4, RPA3 LDHA 3754/4885LDHB 3719/4885NOTUM 3420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.