Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559 | 0.82 | LPL (0.33) | LPLLIPG | |
| SCHEMBL16990403 | 0.73 | LPL (0.36) | LPLLIPGIDO1TDO2CXCR2 | |
| SCHEMBL18233837 | 0.73 | HTR2C (0.33) | — | |
| SCHEMBL21275790 | 0.72 | LPL (0.35) | LPLLIPGIDO1TDO2CXCR2 | |
| SCHEMBL1356283 | 0.70 | KDM4E (0.47) | LPLLIPGIDO1TDO2 | |
| SCHEMBL3928563 | 0.70 | JAK2 (0.33) | — | |
| SCHEMBL1892254 | 0.68 | HTR6 (0.39) | — | |
| SCHEMBL16009573 | 0.68 | HTR6 (0.35) | LPLLIPGCXCR2 | |
| SCHEMBL16651607 | 0.68 | BRD4 (0.41) | LPLLIPGIDO1TDO2 | |
| SCHEMBL16651362 | 0.68 | BRD4 (0.41) | LPLLIPGIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160333015-A1 | 4-Substituted Pyrrolo[2,3-d]pyrimidine Compound and Use Thereof | JIANGSU CAREFREE PHARMACEUTICAL CO., LTD (CN) | 2016-11-17 | — | — | US | disclosed |
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | LPL 4866/4885LIPG 4818/4885IDO1 1522/4885 |
| US-20160333015-A1 | 4-Substituted Pyrrolo[2,3-d]pyrimidine Compound and Use Thereof | JAK1, JAK2, JAK3 | LPL 4683/4885LIPG 4178/4885IDO1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.