Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608999 | 0.88 | NEK1 (0.31) | ADRA1APDE4DNEK1TDP1MMP2 | |
| SCHEMBL6610576 | 0.86 | KDM4E (0.37) | PRKCZPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6610237 | 0.83 | MAPT (0.35) | ADRA1APDE4DNEK1MMP2MMP9 | |
| SCHEMBL6216050 | 0.81 | ALDH1A1 (0.39) | PRKCZPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6609561 | 0.80 | ADRA1A (0.33) | ADRA1APDE4DNEK1MMP2MMP9 | |
| SCHEMBL27462981 | 0.79 | CYP4F2 (0.36) | TDP1ALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL7466413 | 0.76 | ALDH1A1 (0.37) | TDP1MMP2MMP9MMP14PRKCZ | |
| SCHEMBL11113821 | 0.75 | CA12 (0.39) | PRKCIPRKCZPOLBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7478362 | 0.75 | ALDH1A1 (0.36) | TDP1MMP2MMP9MMP14PRKCZ | |
| Hydrochloric Acid SCHEMBL11113817 | 0.74 | CA12 (0.38) | PRKCIPRKCZPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |