Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611018 | 0.85 | SMN1; SMN2 (0.47) | SLC1A3SLC1A2SLC1A1HPGDHTT | |
| SCHEMBL5841099 | 0.85 | ALDH1A1 (0.51) | PARP1SLC1A3SLC1A2SLC1A1HPGD | |
| SCHEMBL6608899 | 0.78 | NPY5R (0.63) | HPGDHTTMEN1KMT2ALMNA | |
| SCHEMBL6609908 | 0.78 | CYP1A2 (0.48) | SLC1A3SLC1A2SLC1A1HPGDALOX15 | |
| SCHEMBL6613964 | 0.78 | CYP1A2 (0.48) | SLC1A3SLC1A2SLC1A1HPGDL3MBTL1 | |
| SCHEMBL6609444 | 0.73 | CYP1A2 (0.45) | HPGDL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL6610739 | 0.72 | SMN1; SMN2 (0.48) | SLC1A3SLC1A2SLC1A1HPGDL3MBTL1 | |
| SCHEMBL6614270 | 0.71 | ACHE (0.44) | L3MBTL1MEN1KMT2ALMNANPC1 | |
| SCHEMBL5841303 | 0.69 | SMN1; SMN2 (0.66) | HPGDHTTL3MBTL1MEN1KMT2A | |
| SCHEMBL11655760 | 0.67 | CYP1A2 (0.73) | SLC1A3SLC1A2SLC1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |