Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylbenzene SCHEMBL9799051 | 0.91 | HSD11B1 (0.47) | HSD11B1ALDH1A1NPC1RAB9ARECQL | |
| Tert-Butylbenzene SCHEMBL28779726 | 0.89 | MAPT (0.53) | HSD11B1ALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL28070081 | 0.87 | HSD17B2 (0.50) | HSD11B1ALDH1A1NPC1RAB9ARECQL | |
| Tert-Butylbenzene SCHEMBL28464198 | 0.87 | TSHR (0.53) | HSD11B1ALDH1A1TDP1MAPK1L3MBTL1 | |
| Tert-Butylbenzene SCHEMBL27713888 | 0.87 | TSHR (0.53) | HSD11B1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL7420437 | 0.85 | NR3C2 (0.57) | ALDH1A1TDP1HSD17B10NR3C2MAPK1 | |
| SCHEMBL27613717 | 0.84 | ALDH1A1 (0.48) | HSD11B1ALDH1A1TDP1HSD17B10NR3C2 | |
| Tert-Butylbenzene SCHEMBL22264597 | 0.84 | MAPK1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1TSHR | |
| Tert-Butylbenzene SCHEMBL22264599 | 0.84 | MAPK1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1TSHR | |
| Tert-Butylbenzene SCHEMBL2568053 | 0.84 | MAPK1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850142-A | Synthesis method of 7Z vitamin D compound | 甘肃皓天医药科技有限责任公司 | 2023-03-28 | — | — | CN | claimed |
| CN-109180478-B | Diphenheptane compounds, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2021-07-20 | — | — | CN | claimed |
| CN-109503693-B | Process for synthesizing Aramchol by using cholic acid as raw material | 合肥工业大学 | 2021-04-06 | — | — | CN | claimed |
| CN-108002732-B | Preparation method of p-tert-butylbenzenesulfonamide type concrete foaming agent | 舒浪平 | 2021-01-26 | — | — | CN | claimed |
| CN-111100044-B | Preparation method of alkyl zinc sulfinate series compounds | 鹤壁元昊化工有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-102603630-A | O-aminobenzoic acid sulfonylation derivative as well as preparation method and application thereof | UNIV BEIJING SCIENCE & TECH | 2012-07-25 | — | — | CN | claimed |
| CN-101100461-B | Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof | PENGCHENG REN | 2012-04-18 | — | — | CN | claimed |
| CN-101100461-A | Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof | PENGCHENG REN (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-116120261-B | Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound | 浙大宁波理工学院 | 2024-01-23 | — | — | CN | disclosed |
| CN-116120261-A | Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound | 浙大宁波理工学院 | 2023-05-16 | — | — | CN | disclosed |
| CN-115850142-A | Synthesis method of 7Z vitamin D compound | 甘肃皓天医药科技有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113264937-B | 4-aminopyrazolo [3,4-d ] pyrimidine derivative and application thereof | 南开大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-110483272-B | Novel method for asymmetric synthesis of (1S,2S) -2-fluorocyclopropanecarboxylic acid by catalysis of chiral rhodium catalyst | 广州康瑞泰药业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-112264012-B | Magnetic silicon-lithium catalyst and preparation method and application thereof | 江南大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-1165143-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1165144-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1162596-A | Antiarrhythmic Agents | AMERICAN CYANAMID CO (US) | 1997-10-22 | — | — | CN | disclosed |
| CN-1146990-A | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 1997-04-09 | — | — | CN | disclosed |
| CN-1111242-A | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1995-11-08 | — | — | CN | disclosed |
| CN-1066266-A | PHOSPHOSULFONATE HERBICIDES | ROHM & HAAS (US) | 1992-11-18 | — | — | CN | disclosed |